Wednesday, 21 March 2012

Emend for Injection pimozide


Pronunciation: FOS-ap-RE-pi-tant
Generic Name: Fosaprepitant
Brand Name: Emend for Injection


Emend for Injection pimozide is used for:

Preventing nausea and vomiting associated with certain types of cancer medicines (chemotherapy). It is used in combination with other medicines. It may also be used for other conditions as determined by your doctor.


Emend for Injection pimozide is an antiemetic. It works by blocking certain substances in the brain, which helps to prevent nausea and vomiting.


Do NOT use Emend for Injection pimozide if:


  • you are allergic to any ingredient in Emend for Injection pimozide, or if you are allergic to aprepitant or polysorbate 80

  • you are taking astemizole, cisapride, pimozide, or terfenadine

Contact your doctor or health care provider right away if any of these apply to you.



Before using Emend for Injection pimozide:


Some medical conditions may interact with Emend for Injection pimozide. Tell your doctor or pharmacist if you have any medical conditions, especially if any of the following apply to you:


  • if you are pregnant, planning to become pregnant, or are breast-feeding

  • if you are taking any prescription or nonprescription medicine, herbal preparation, or dietary supplement

  • if you have allergies to medicines, foods, or other substances

  • if you have liver problems

  • if you currently have nausea or vomiting

Some MEDICINES MAY INTERACT with Emend for Injection pimozide. Tell your health care provider if you are taking any other medicines, especially any of the following:


  • Azole antifungals (eg, ketoconazole), diltiazem, HIV protease inhibitors (eg, ritonavir), macrolide antibiotics (eg, clarithromycin), nefazodone, or troleandomycin because they may increase the risk of Emend for Injection pimozide's side effects

  • Carbamazepine or rifampin because they may decrease Emend for Injection pimozide's effectiveness

  • Astemizole, benzodiazepines (eg, alprazolam), cisapride, corticosteroids (eg, dexamethasone), ifosfamide, narcotic pain medicines (eg, fentanyl), pimozide, terfenadine, vinblastine, or vincristine because the risk of their side effects may be increased by Emend for Injection pimozide

  • Anticoagulants (eg, warfarin), hormonal contraceptives (eg, birth control pills), paroxetine, phenytoin, or tolbutamide because their effectiveness may be decreased by Emend for Injection pimozide

This may not be a complete list of all interactions that may occur. Ask your health care provider if Emend for Injection pimozide may interact with other medicines that you take. Check with your health care provider before you start, stop, or change the dose of any medicine.


How to use Emend for Injection pimozide:


Use Emend for Injection pimozide as directed by your doctor. Check the label on the medicine for exact dosing instructions.


  • An extra patient leaflet is available with Emend for Injection pimozide. Talk to your pharmacist if you have questions about this information.

  • Tell your doctor if you already have nausea or vomiting before you receive Emend for Injection pimozide.

  • Emend for Injection pimozide is usually given as an injection at your doctor's office, hospital, or clinic 30 minutes before chemotherapy treatment.

  • If you miss a dose of Emend for Injection pimozide, contact your doctor immediately.

Ask your health care provider any questions you may have about how to use Emend for Injection pimozide.



Important safety information:


  • Emend for Injection pimozide may cause dizziness. These effects may be worse if you take it with alcohol or certain medicines. Use Emend for Injection pimozide with caution. Do not drive or perform other possibly unsafe tasks until you know how you react to it.

  • Do not drink alcohol or use medicines that may cause drowsiness (eg, sleep aids, muscle relaxers) while you are using Emend for Injection pimozide; it may add to their effects. Ask your pharmacist if you have questions about which medicines may cause drowsiness.

  • Hormonal birth control (eg, birth control pills) may not work as well while you are using Emend for Injection pimozide. To prevent pregnancy, be sure to use an extra form of birth control (eg, condoms) while using Emend for Injection pimozide and for 1 month following the last dose of Emend for Injection pimozide.

  • Lab tests, including liver function, kidney function, and white blood cell counts, may be performed while you use Emend for Injection pimozide. These tests may be used to monitor your condition or check for side effects. Be sure to keep all doctor and lab appointments.

  • Use Emend for Injection pimozide with extreme caution in CHILDREN; safety and effectiveness in children have not been confirmed.

  • PREGNANCY and BREAST-FEEDING: If you become pregnant, contact your doctor. You will need to discuss the benefits and risks of using Emend for Injection pimozide while you are pregnant. It is not known if Emend for Injection pimozide is found in breast milk. Do not breast-feed while taking Emend for Injection pimozide.


Possible side effects of Emend for Injection pimozide:


All medicines may cause side effects, but many people have no, or minor, side effects. Check with your doctor if any of these most COMMON side effects persist or become bothersome:



Constipation; diarrhea; dizziness; headache; hiccups; loss of appetite; nausea; pain or hardening at the injection site; tiredness; upset stomach; weakness.



Seek medical attention right away if any of these SEVERE side effects occur:

Severe allergic reactions (rash; hives; itching; difficulty breathing; tightness in the chest; swelling of the mouth, face, lips, or tongue); fast or irregular heartbeat; fever; shortness of breath; sore throat.



This is not a complete list of all side effects that may occur. If you have questions about side effects, contact your health care provider. Call your doctor for medical advice about side effects. To report side effects to the appropriate agency, please read the Guide to Reporting Problems to FDA.


See also: Emend side effects (in more detail)


If OVERDOSE is suspected:


Contact 1-800-222-1222 (the American Association of Poison Control Centers), your local poison control center, or emergency room immediately. Symptoms may include drowsiness; headache.


Proper storage of Emend for Injection pimozide:

Emend for Injection pimozide is usually handled and stored by a health care provider. If you are using Emend for Injection pimozide at home, store Emend for Injection pimozide as directed by your pharmacist or health care provider.


General information:


  • If you have any questions about Emend for Injection pimozide, please talk with your doctor, pharmacist, or other health care provider.

  • Emend for Injection pimozide is to be used only by the patient for whom it is prescribed. Do not share it with other people.

  • If your symptoms do not improve or if they become worse, check with your doctor.

  • Check with your pharmacist about how to dispose of unused medicine.

This information is a summary only. It does not contain all information about Emend for Injection pimozide. If you have questions about the medicine you are taking or would like more information, check with your doctor, pharmacist, or other health care provider.



Issue Date: February 1, 2012

Database Edition 12.1.1.002

Copyright © 2012 Wolters Kluwer Health, Inc.

More Emend for Injection resources


  • Emend for Injection Side Effects (in more detail)
  • Emend for Injection Use in Pregnancy & Breastfeeding
  • Emend for Injection Drug Interactions
  • Emend for Injection Support Group
  • 0 Reviews for Emend - Add your own review/rating


Compare Emend for Injection with other medications


  • Nausea/Vomiting, Chemotherapy Induced

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