Thursday 23 July 2009

Gelobufen




Gelobufen may be available in the countries listed below.


Ingredient matches for Gelobufen



Ibuprofen

Ibuprofen is reported as an ingredient of Gelobufen in the following countries:


  • Spain

International Drug Name Search

Wednesday 22 July 2009

Ciprofat




Ciprofat may be available in the countries listed below.


Ingredient matches for Ciprofat



Ciprofloxacin

Ciprofloxacin hydrochloride (a derivative of Ciprofloxacin) is reported as an ingredient of Ciprofat in the following countries:


  • Germany

International Drug Name Search

Monday 20 July 2009

Intermezzo


Intermezzo is a brand name of zolpidem, approved by the FDA in the following formulation(s):


INTERMEZZO (zolpidem tartrate - tablet; sublingual)



  • Manufacturer: PURDUE PHARMA

    Approval date: November 23, 2011

    Strength(s): 1.75MG, 3.5MG [RLD]

Has a generic version of Intermezzo been approved?


No. There is currently no therapeutically equivalent version of Intermezzo available.


Note: Fraudulent online pharmacies may attempt to sell an illegal generic version of Intermezzo. These medications may be counterfeit and potentially unsafe. If you purchase medications online, be sure you are buying from a reputable and valid online pharmacy. Ask your health care provider for advice if you are unsure about the online purchase of any medication.

See also: About generic drugs.




Related Patents


Patents are granted by the U.S. Patent and Trademark Office at any time during a drug's development and may include a wide range of claims.




  • Compositions for delivering hypnotic agents across the oral mucosa and methods of use thereof
    Patent 7,658,945
    Issued: February 9, 2010
    Inventor(s): Singh; Nikhilesh N.
    Assignee(s): Transcept Pharmaceuticals, Inc.
    The present invention provides novel compositions for the delivery of a hypnotic agent across the oral mucosa. In particular, the buffer system in the compositions of the present invention raises the pH of saliva to a pH greater than about 7.8, thereby facilitating the substantially complete conversion of the hypnotic agent from its ionized to its un-ionized form. As a result, the dose of hypnotic agent is rapidly and efficiently absorbed by the oral mucosa with surprisingly low inter-subject variability. Furthermore, delivery of the hypnotic agent across the oral mucosa advantageously bypasses hepatic first pass metabolism of the drug and avoids enzymatic degradation of the drug within the gastrointestinal tract. Methods for using the compositions of the present invention for treating sleep disorders such as insomnia are also provided.
    Patent expiration dates:

    • April 15, 2027
      ✓ 
      Patent use: METHOD FOR TREATING INSOMNIA
      ✓ 
      Drug product




  • Compositions for delivering hypnotic agents across the oral mucosa and methods of use thereof
    Patent 7,682,628
    Issued: March 23, 2010
    Inventor(s): Singh; Nikhilesh N.
    Assignee(s): Transcept Pharmaceuticals, Inc.
    The present invention provides novel compositions for the delivery of a hypnotic agent across the oral mucosa. In particular, the buffer system in the compositions of the present invention raises the pH of saliva to a pH greater than about 7.8, thereby facilitating the substantially complete conversion of the hypnotic agent from its ionized to its un-ionized form. As a result, the dose of hypnotic agent is rapidly and efficiently absorbed by the oral mucosa with surprisingly low inter-subject variability. Furthermore, delivery of the hypnotic agent across the oral mucosa advantageously bypasses hepatic first pass metabolism of the drug and avoids enzymatic degradation of the drug within the gastrointestinal tract. Methods for using the compositions of the present invention for treating sleep disorders such as insomnia are also provided.
    Patent expiration dates:

    • February 16, 2025
      ✓ 
      Patent use: METHOD FOR TREATING INSOMNIA



Related Exclusivities

Exclusivity is exclusive marketing rights granted by the FDA upon approval of a drug and can run concurrently with a patent or not. Exclusivity is a statutory provision and is granted to an NDA applicant if statutory requirements are met.

  • Exclusivity expiration dates:
    • November 23, 2014 - NEW PRODUCT

See also...

  • Intermezzo Consumer Information (Drugs.com)
  • Intermezzo Consumer Information (Cerner Multum)
  • Zolpidem Consumer Information (Drugs.com)
  • Zolpidem Consumer Information (Wolters Kluwer)
  • Zolpidem Extended-Release Tablets Consumer Information (Wolters Kluwer)
  • Zolpidem Oral Spray Consumer Information (Wolters Kluwer)
  • Zolpidem Consumer Information (Cerner Multum)
  • Zolpidem Oral, Oromucosal Advanced Consumer Information (Micromedex)
  • Zolpidem Tartrate AHFS DI Monographs (ASHP)

Saturday 18 July 2009

Benzocaine Liquid


Pronunciation: BEN-zoe-kane
Generic Name: Benzocaine
Brand Name: Anbesol


Benzocaine Liquid is used for:

Treating pain from mouth and gum irritations (eg, canker sores). It may also be used for other conditions as determined by your doctor.


Benzocaine Liquid in a local anesthetic. It works by numbing sensitive and painful areas.


Do NOT use Benzocaine Liquid if:


  • you are allergic to any ingredient in Benzocaine Liquid or to other local anesthetics (eg, butacaine, procaine)

Contact your doctor or health care provider right away if any of these apply to you.



Before using Benzocaine Liquid:


Some medical conditions may interact with Benzocaine Liquid. Tell your doctor or pharmacist if you have any medical conditions, especially if any of the following apply to you:


  • if you are pregnant, planning to become pregnant, or are breast-feeding

  • if you are taking any prescription or nonprescription medicine, herbal preparation, or dietary supplement

  • if you have allergies to medicines, foods, or other substances

Some MEDICINES MAY INTERACT with Benzocaine Liquid. Because little, if any, of Benzocaine Liquid is absorbed into the blood, the risk of it interacting with another medicine is low.


Ask your health care provider if Benzocaine Liquid may interact with other medicines that you take. Check with your health care provider before you start, stop, or change the dose of any medicine.


How to use Benzocaine Liquid:


Use Benzocaine Liquid as directed by your doctor. Check the label on the medicine for exact dosing instructions.


  • An adult should supervise the use of Benzocaine Liquid if the patient is a CHILD younger than 12 years old.

  • To use a dose of Benzocaine Liquid, follow the instructions provided by your doctor or on the product label.

  • Wash your hands before and after you use Benzocaine Liquid. Apply medicine to the affected area by using cotton, a cotton swab, or a clean fingertip.

  • Do not eat or drink for at least 1 hour after using Benzocaine Liquid.

  • Do not use Benzocaine Liquid within 1 hour of your previous dose or use more than 4 times per day, unless your doctor or dentist tells you otherwise.

  • If you miss a dose of Benzocaine Liquid, use it as soon as you remember. Continue to use it as directed by your doctor or on the package label.

Ask your health care provider any questions you may have about how to use Benzocaine Liquid.



Important safety information:


  • Do not get Benzocaine Liquid in your eyes. If you get it in your eyes, rinse at once with cool water.

  • Do NOT use more than the recommended dose or use for longer than 7 days without checking with your doctor or dentist.

  • If your symptoms do not get better within 7 days or if they get worse, check with your doctor.

  • Contact your doctor if you have persistent or worsening pain, redness, or irritation, or if you develop swelling, rash, or a fever. Tell your doctor if you have mouth sores that keep coming back.

  • Benzocaine Liquid may cause harm if more than the amount used to treat pain is swallowed. If this occurs, contact your poison control center or emergency room right away.

  • Benzocaine Liquid should not be used in CHILDREN younger than 2 years old without checking with the child's doctor or dentist; safety and effectiveness in these children have not been confirmed.

  • PREGNANCY and BREAST-FEEDING: It is not known if Benzocaine Liquid can cause harm to the fetus. If you become pregnant, contact your doctor. You will need to discuss the benefits and risks of using Benzocaine Liquid while you are pregnant. It is not known if Benzocaine Liquid is found in breast milk. If you are or will be breast-feeding while you use Benzocaine Liquid, check with your doctor. Discuss any possible risks to your baby.


Possible side effects of Benzocaine Liquid:


All medicines may cause side effects, but many people have no, or minor, side effects. No COMMON side effects have been reported with this product. Seek medical attention right away if any of these SEVERE side effects occur:



Severe allergic reactions (rash; hives; itching; difficulty breathing; tightness in the chest; swelling of the mouth, face, lips, or tongue); mouth burning, irritation, redness, swelling, or tenderness.



This is not a complete list of all side effects that may occur. If you have questions about side effects, contact your health care provider. Call your doctor for medical advice about side effects. To report side effects to the appropriate agency, please read the Guide to Reporting Problems to FDA.



If OVERDOSE is suspected:


Contact 1-800-222-1222 (the American Association of Poison Control Centers), your local poison control center, or emergency room immediately. Benzocaine Liquid may cause harm if more than is used for pain is swallowed. Symptoms may include blue skin or lips; trouble breathing.


Proper storage of Benzocaine Liquid:

Store Benzocaine Liquid at room temperature, between 68 and 77 degrees F (20 and 25 degrees C). Store away from heat, moisture, and light. Keep Benzocaine Liquid out of the reach of children and away from pets.


General information:


  • If you have any questions about Benzocaine Liquid, please talk with your doctor, pharmacist, or other health care provider.

  • Benzocaine Liquid is to be used only by the patient for whom it is prescribed. Do not share it with other people.

  • If your symptoms do not improve or if they become worse, check with your doctor.

  • Check with your pharmacist about how to dispose of unused medicine.

This information is a summary only. It does not contain all information about Benzocaine Liquid. If you have questions about the medicine you are taking or would like more information, check with your doctor, pharmacist, or other health care provider.



Issue Date: February 1, 2012

Database Edition 12.1.1.002

Copyright © 2012 Wolters Kluwer Health, Inc.

More Benzocaine resources


  • Benzocaine Use in Pregnancy & Breastfeeding
  • Benzocaine Support Group
  • 6 Reviews for Benzocaine - Add your own review/rating


Compare Benzocaine with other medications


  • Anal Itching
  • Anesthesia
  • Aphthous Ulcer
  • Burns, External
  • Cold Sores
  • Hemorrhoids
  • Oral and Dental Conditions
  • Pain
  • Pruritus
  • Sunburn
  • Tonsillitis/Pharyngitis

Oralmuv




Oralmuv may be available in the countries listed below.


Ingredient matches for Oralmuv



Lamivudine

Lamivudine is reported as an ingredient of Oralmuv in the following countries:


  • Argentina

International Drug Name Search

Wednesday 8 July 2009

Fovas




Fovas may be available in the countries listed below.


Ingredient matches for Fovas



Fosinopril

Fosinopril sodium salt (a derivative of Fosinopril) is reported as an ingredient of Fovas in the following countries:


  • India

International Drug Name Search

Tuesday 7 July 2009

Germitol




Germitol may be available in the countries listed below.


In some countries, this medicine may only be approved for veterinary use.

Ingredient matches for Germitol



Benzalkonium Chloride

Benzalkonium chloride (a derivative of Benzalkonium) is reported as an ingredient of Germitol in the following countries:


  • Japan

Povidone Iodine

Povidone-Iodine is reported as an ingredient of Germitol in the following countries:


  • Italy

International Drug Name Search

Carvedilol LPH




Carvedilol LPH may be available in the countries listed below.


Ingredient matches for Carvedilol LPH



Carvedilol

Carvedilol is reported as an ingredient of Carvedilol LPH in the following countries:


  • Romania

International Drug Name Search

Sunday 5 July 2009

Bactexina




Bactexina may be available in the countries listed below.


Ingredient matches for Bactexina



Azithromycin

Azithromycin is reported as an ingredient of Bactexina in the following countries:


  • Dominican Republic

International Drug Name Search

Saturday 4 July 2009

Oxaliplatin


Pronunciation: ox-AL-ih-plah-tin
Generic Name: Oxaliplatin
Brand Name: Eloxatin

Use Oxaliplatin only under close medical supervision. Oxaliplatin may rarely cause severe and sometimes fatal allergic reactions during administration. Notify your doctor immediately if you experience signs of an allergic reaction such as rash, hives, itching, dizziness, swelling, excessive sweating, chest pain, disorientation, shortness of breath, trouble breathing, or fainting.





Oxaliplatin is used for:

Treating advanced cancer of the colon or rectum in certain patients. It is usually used in combination with other medicines.


Oxaliplatin is an antineoplastic. It works by killing cancer cells and slowing tumor growth.


Do NOT use Oxaliplatin if:


  • you are allergic to any ingredient in Oxaliplatin or to another platinum product (eg, cisplatin, carboplatin)

  • you have certain lung problems (eg, pulmonary fibrosis, interstitial lung disease) or bone marrow disease

Contact your doctor or health care provider right away if any of these apply to you.



Before using Oxaliplatin:


Some medical conditions may interact with Oxaliplatin. Tell your doctor or pharmacist if you have any medical conditions, especially if any of the following apply to you:


  • if you are pregnant, planning to become pregnant, or are breast-feeding

  • if you are taking any prescription or nonprescription medicine, herbal preparation, or dietary supplement

  • if you have allergies to medicines, foods, or other substances

  • if you have kidney or liver problems, blood disorders (eg, anemia), or nerve disorders

Some MEDICINES MAY INTERACT with Oxaliplatin. Tell your health care provider if you are taking any other medicines, especially any of the following:


  • Anticoagulants (eg, warfarin) because the risk of bleeding may be increased

  • Medicines that may harm the kidney (eg, aminoglycoside antibiotics [eg, gentamicin], amphotericin B, cyclosporine, nonsteroidal anti-inflammatory drugs [NSAIDs] [eg, ibuprofen], tacrolimus, vancomycin) because the risk of Oxaliplatin's side effects may be increased. Ask your doctor if you are unsure if any of your medicines might harm the kidney

This may not be a complete list of all interactions that may occur. Ask your health care provider if Oxaliplatin may interact with other medicines that you take. Check with your health care provider before you start, stop, or change the dose of any medicine.


How to use Oxaliplatin:


Use Oxaliplatin as directed by your doctor. Check the label on the medicine for exact dosing instructions.


  • An extra patient leaflet is available with Oxaliplatin. Talk to your pharmacist if you have questions about this information.

  • Oxaliplatin is usually administered as an injection at your doctor's office, hospital, or clinic.

  • Do not use Oxaliplatin if it contains particles, is cloudy or discolored, or if the vial is cracked or damaged.

  • If nausea, vomiting, or loss of appetite occurs, ask your doctor or pharmacist for ways to lessen these effects. Also, other medicines may be given before and after therapy with Oxaliplatin to help reduce these effects.

  • It is important to take each dose as scheduled. If you must miss a dose, contact your doctor right away.

Ask your health care provider any questions you may have about how to use Oxaliplatin.



Important safety information:


  • Oxaliplatin may cause dizziness, fatigue, balance problems, temporary vision loss, or other vision changes. These effects may be worse if you take it with alcohol or certain medicines. Use Oxaliplatin with caution. Do not drive or perform other possibly unsafe tasks until you know how you react to it.

  • If vomiting or diarrhea occurs, you will need to take care not to become dehydrated. Contact your doctor for instructions.

  • Oxaliplatin may reduce the number of clot-forming cells (platelets) in your blood. Avoid activities that may cause bruising or injury. Tell your doctor if you have unusual bruising or bleeding. Tell your doctor if you have dark, tarry, or bloody stools.

  • Oxaliplatin may lower the ability of your body to fight infection. Avoid contact with people who have colds or other infections. Do not touch your eyes or the inside of your nose unless you have thoroughly washed your hands first.

  • Do not receive a live vaccine (eg, measles, mumps) while you are taking Oxaliplatin. Talk with your doctor before you receive any vaccine.

  • Some patients using Oxaliplatin have developed severe and sometimes fatal lung problems. Tell your doctor right away if you develop dry cough, shortness of breath, or chest pain.

  • Oxaliplatin may cause burning, numbness, or tingling in the hands or feet, or around the mouth or throat. It may also cause jaw spasms, odd feelings in your tongue, joint or eye pain, or chest pressure. Exposure to cold temperatures or cold objects may make these symptoms worse. Avoid drinking cold drinks and ice while receiving Oxaliplatin. Cover exposed skin before exposing yourself to cold temperatures or cold objects. Tell your doctor if these persist or become bothersome.

  • You can reduce sensitivity to cold temperatures or objects by doing the following: cover yourself with a blanket while receiving medicine; do not breathe deeply when exposed to cold air; wear warm clothing in cold weather at all times; cover your mouth and nose with a scarf or a ski cap to warm the air that goes into your lungs; wear gloves when removing items from the freezer and refrigerator or when touching car doors, mailboxes, or other metal objects; drink lukewarm fluids; drink beverages with a straw; do not use ice chips if you have nausea or mouth sores; do not put ice packs on your body; do not run the air conditioning at high levels in the house or car during hot weather; if you get cold, warm up only the cold part of your body; warm cold hands up with warm water.

  • Diabetes patients - Oxaliplatin may affect your blood sugar. Check blood sugar levels closely. Ask your doctor before you change the dose of your diabetes medicine.

  • Women who may become pregnant should use an effective form of birth control while they are using Oxaliplatin. Talk with your doctor if you have questions about effective birth control.

  • Lab tests, including complete blood cell counts and liver function, may be performed while you use Oxaliplatin. These tests may be used to monitor your condition or check for side effects. Be sure to keep all doctor and lab appointments.

  • Use Oxaliplatin with caution in the ELDERLY; they may be more sensitive to its effects, especially diarrhea, dehydration, low potassium levels, fatigue, and fainting.

  • Oxaliplatin should be used with extreme caution in CHILDREN; safety and effectiveness in children have not been confirmed.

  • PREGNANCY and BREAST-FEEDING: Oxaliplatin has been shown to cause harm to the fetus. Do not become pregnant while you are using it. If you think you may be pregnant, contact your doctor. You will need to discuss the benefits and risks of using Oxaliplatin while you are pregnant. It is unknown if Oxaliplatin is excreted in breast milk. Do not breast-feed while taking Oxaliplatin.


Possible side effects of Oxaliplatin:


All medicines may cause side effects, but many people have no, or minor, side effects. Check with your doctor if any of these most COMMON side effects persist or become bothersome:



Constipation; decreased appetite; diarrhea; dizziness; fatigue; gas; hair loss; headache; heartburn; hiccups; increased tears; muscle or joint aches; nausea; pain, redness, or swelling at the injection site; runny nose; taste changes; trouble sleeping; vomiting; weight loss.



Seek medical attention right away if any of these SEVERE side effects occur:

Severe allergic reactions (rash; hives; itching; difficulty breathing; tightness in the chest; swelling of the mouth, face, lips, or tongue); blood in the urine; calf or groin pain, swelling, or redness; change in the amount of urine produced; chest pain or pressure; confusion, slurred speech, or one-sided weakness; coughing up blood; disorientation; excessive sweating; fainting; flushing; mouth sores or swelling; nosebleeds; red, swollen, blistered, or peeling skin; severe or persistent diarrhea or vomiting; severe or persistent dizziness; severe or persistent pain, swelling, or redness at the injection site; severe or persistent tiredness or weakness; shortness of breath; sudden, severe headache; swelling of the hands, ankles, or feet; symptoms of dehydration (eg, very dry eyes, mouth, or skin; unusual thirst); symptoms of infection (eg, fever, chills, or sore throat; painful urination; productive cough); symptoms of liver problems (eg, yellowing of the skin or eyes; dark urine; pale stools; persistent nausea, stomach pain, or loss of appetite); symptoms of low potassium levels (eg, irregular heartbeat, muscle pain or cramps); symptoms of stomach or bowel bleeding (eg, black, tarry stools; vomit that looks like coffee grounds); trouble walking, swallowing, speaking, or performing other daily tasks (eg, writing, buttoning); unusual bruising or bleeding; vision loss or other vision changes.



This is not a complete list of all side effects that may occur. If you have questions about side effects, contact your health care provider. Call your doctor for medical advice about side effects. To report side effects to the appropriate agency, please read the Guide to Reporting Problems to FDA.


See also: Oxaliplatin side effects (in more detail)


If OVERDOSE is suspected:


Contact 1-800-222-1222 (the American Association of Poison Control Centers), your local poison control center, or emergency room immediately. Symptoms may include chest pain; diarrhea; easy bruising or bleeding; fatigue; muscle spasms in the face; persistent change in bowel habits; persistent sore throat or fever; numbness or tingling in the arms, hands, legs, or feet; severe nausea and vomiting; shortness of breath; swelling in the mouth; swollen stomach; very slow heartbeat; wheezing.


Proper storage of Oxaliplatin:

Oxaliplatin is usually handled and stored by a health care provider. If you are using Oxaliplatin at home, store Oxaliplatin as directed by your pharmacist or health care provider. Keep Oxaliplatin out of the reach of children and away from pets.


General information:


  • If you have any questions about Oxaliplatin, please talk with your doctor, pharmacist, or other health care provider.

  • Oxaliplatin is to be used only by the patient for whom it is prescribed. Do not share it with other people.

  • If your symptoms do not improve or if they become worse, check with your doctor.

  • Check with your pharmacist about how to dispose of unused medicine.

This information is a summary only. It does not contain all information about Oxaliplatin. If you have questions about the medicine you are taking or would like more information, check with your doctor, pharmacist, or other health care provider.



Issue Date: February 1, 2012

Database Edition 12.1.1.002

Copyright © 2012 Wolters Kluwer Health, Inc.

More Oxaliplatin resources


  • Oxaliplatin Side Effects (in more detail)
  • Oxaliplatin Use in Pregnancy & Breastfeeding
  • Oxaliplatin Drug Interactions
  • Oxaliplatin Support Group
  • 1 Review for Oxaliplatin - Add your own review/rating


  • Oxaliplatin Prescribing Information (FDA)

  • Oxaliplatin Professional Patient Advice (Wolters Kluwer)

  • Oxaliplatin Monograph (AHFS DI)

  • oxaliplatin Intravenous Advanced Consumer (Micromedex) - Includes Dosage Information

  • Eloxatin Prescribing Information (FDA)

  • Eloxatin Consumer Overview



Compare Oxaliplatin with other medications


  • Colorectal Cancer